ICE Bioscience's Custom Protein Expression and Purification Services are built upon three foundational pillars, designed to deliver proteins of the highest quality for your drug discovery needs. These modules reflect our commitment to scientific excellence and operational efficiency.

Protein Expression Platform

▪ E. coli Expression: A fast and cost-effective system for high-yield protein production.

▪ Insect Expression: Utilized for complex protein production which requires post-translational modifications.

▪ Mammalian Cell Expression: The premium choice for producing proteins with human-like post-translational modifications, ensuring high biological activity.

Each expression system is selected based on the specific needs of the target protein to ensure optimal yield and functionality.

Protein Purification Platform

▪ Manual Affinity Chromatography: Precise and tailored purification to capture the protein of interest.

▪ AKTA Automation: Advanced chromatography systems that enable automated, high-throughput purification with affinity, ion exchange, and size exclusion techniques.

Our purification strategies are fine-tuned to the unique properties of each protein, ensuring purity and integrity.

Quality Control

Routine Tests:

▪ SDS-PAGE: To verify protein purity.

▪ SEC-HPLC: For assessing molecular size distribution.

▪ LCMS: To confirm protein mass and identity.

Biophysics and Biochemical Assays:

▪ SPR (Surface Plasmon Resonance): For real-time monitoring of protein interactions and kinetics.

▪ TSA (Thermal Shift Assay): To evaluate protein stability.

▪ Biochemical Activity Fitting: Quantitative assessment of protein function through enzyme kinetics and binding assays.

Our comprehensive Quality Control Platform ensures that every protein meets stringent quality standards, providing you with reliable data for functional assays.

Choose ICE Bioscience for Precision and Reliability

Leverage our advanced platforms to accelerate your research with confidence. ICE Bioscience's meticulous approach, from expression to purification and quality control, guarantees proteins that meet your research's highest demands. Contact us to initiate your custom protein project with a partner dedicated to scientific rigor and quality excellence.