ICE Bioscience offers a comprehensive range of NanoBRET Target Engagement (TE) Assays. These assays are designed to provide real-time, quantitative data on the interaction between a test compound and an expressed target protein within live cells, making them a valuable tool for drug discovery and development processes.

The NanoBRET TE technology capitalizes on bioluminescence resonance energy transfer to measure the proximity between a NanoLuc luciferase-tagged target protein and a fluorescently labeled tracer molecule that competes with test compounds. This approach allows for precise measurement of drug-target engagement in a natural cellular context, enhancing the relevance of the results to physiological conditions.

Our service includes a variety of assays tailored to different target classes and therapeutic areas, enabling researchers to select the most suitable assay for their specific needs. 

✅ Rapid Turnaround Time: We offer an exceptionally quick turnaround time of just one week, enabling faster progress in research and development efforts.

✅ Wide Range of Assays: Our service includes nearly 200 different NanoBRET TE Assays, providing a comprehensive selection for diverse research needs.

✅ Customizable Panels: We offer the flexibility to customize assay panels, allowing researchers to tailor their studies with specific combinations of multiple assays for enhanced analytical depth.

For further details about specific assays or to discuss how our NanoBRET TE Assays can support your research, please feel free to contact our customer support team.