1. In vivo pharmacology: related to the nervous system

In vivo pharmacology is to evaluate the efficacy and safety of compounds by studying their effects and mechanisms in animals.

Research contents :

Integrated screening of antiepileptic drugs. (Ion channel targets - in vitro epilepsy model - in vivo epilepsy model)

Sleep activity detection.

Muscle tension detection. (Channel target -ex vivo detection - in vivo detection)

Nerve conduction velocity.

2.Disease type: Neuroscience

The nervous system is an important link to maintain the homeostasis of the body. If it is damaged or destroyed, it will cause a variety of nervous system disease. Nervous system disease is a kind of disease with complex etiology, easy recurrence and difficult to be diagnosed in time. A large number of studies have shown that early treatment of Nervous system disease will significantly improve the drug treatment effect and improve the quality of life of patients, so it is a potential research direction to find biomarkers closely related to the early clinical symptoms of diseases. In addition, because some patients show strong resistance to existing drugs, new Drug development is still a research hotspot in the future.

2.1 Neuropharmacology

Neuropharmacology is the science that studies the effects and applications of drugs and endogenous active substances on the nervous system. It often focuses on specific target areas or certain target functions in the brain, and is characterized by comprehensive research of various disciplines and technologies. It interprets the effects and mechanisms of nervous system drugs from different levels, such as cellular and molecular levels.

2.2 Neurobiology

Neurobiology is a science that studies the molecular composition and structure of nerve cells and how nerve cells form functional circuits through synaptic connections to process information and mediate behavior.

2.3 Neuroimmunology

Neuroimmunology is a research field that combines neuroscience and immunology. The foundation of neuroimmune regulation is the structural pathway or pathway of signal transmission between the nervous system and the immune system.

2.4 Neuroelectrophysiology

Neuroelectrophysiology is a method that uses electrophysiological instruments, microelectrodes, Voltage clamp and Patch clamp techniques to record or measure the changes of Membrane potential, conduction velocity and Ion channel activities of the whole animal or isolated organ tissues, nerves and cell Ion channel.