The cell derived xenograft (CDX) model is a type of tumor research tool built on the basis of tumor cell xenograft models, and it is a crucial step in evaluating the efficacy and safety of new drugs. ICE has a powerful cell bank that can provide suitable CDX models to customers promptly to test the effectiveness of drugs. Screening and evaluating new drugs for various tumors such as lung, liver, and brain can help accelerate the development and launch process of new drugs.

1.Common Cell Line CDX Model

The CDX model can be used to study common tumor types, such as colorectal cancer and breast cancer. The model can help scientists evaluate the efficacy and safety of new drugs in vivo and accelerate the process of new drug development. In addition, the model can be used to study the biological properties of tumors, treatment resistance mechanisms and other aspects.

2.Engineered cell line CDX Model

Through the construction of point mutant cell line CDX models, the therapeutic efficacy and safety of new drugs targeting these specific targets can be evaluated in vivo, providing more effective diagnostic, therapeutic and preventive strategies for precision medicine. In addition, point mutant cell line CDX models can also be used to study drug resistance mechanisms, tumor microenvironment and other issues, which can help to understand the biological characteristics of tumors in depth and provide more systematic and refined support for the development of innovative drugs.

3.Orthotopic Tumor Models

Fluorescent cell-based in situ transplantation model is an experimental animal model used to study tumor growth and metastasis. This model uses cells labeled with fluorescent tags to form a fluorescently labeled tumor in situ transplantation model by injecting fluorescently labeled cells in vivo or in vitro, which can be used to study various aspects of tumor growth, metastasis, and treatment efficacy. ICE has the IVIS Lumina III in vivo imaging system and various orthotopic model building techniques that can quickly complete the construction of fluorescent cell-based in vivo models and drug efficacy evaluation experiments.