EN CN


Target Based Assays

Return

ATPases

ATPase Assay Platform
ATPase Activity Assays for Drug Discovery

ATPases are essential enzymes that catalyze the hydrolysis of ATP into ADP and inorganic phosphate. This reaction releases energy required for a wide range of cellular processes, including muscle contraction, ion transport, and cellular signaling. Dysregulation of ATPase activity is associated with diseases such as neurodegenerative disorders, cancer, and cardiovascular conditions.

ICE Bioscience provides ATPase activity assays for the investigation of kinesin motor proteins and VCP-related biology, supporting the evaluation of ATPase inhibitors in discovery-stage research.

Target Biology
Kinesin and VCP ATPase research
01 · KINESIN ATPASES

Kinesin ATPases are motor proteins responsible for intracellular transport and cell division, particularly during mitosis. Aberrant kinesin expression is linked to dysregulated mitosis in various cancers, making kinesins important therapeutic targets.

02 · VCP ATPASE

VCP (Valosin-Containing Protein), also known as p97, participates in diverse cellular processes, including protein degradation and stress responses. Its association with multiple cancer types makes VCP regulation an important area of therapeutic research.

Assay Technology
ADP-Glo ATPase activity measurement

Our ATPase assay service employs the ADP-Glo technology, a sensitive and precise method for measuring ATPase activity. The assay quantifies the amount of ADP generated during ATP hydrolysis, providing a direct readout of enzymatic activity and enabling the evaluation of potential ATPase inhibitors.

Available Assays
Kinesin and VCP target panel
TargetSynonymsReference CompoundAssay Format
KIF2MCAKAMG650ADP-Glo
KIF3CKlp68DAMG650ADP-Glo
KIFC3/AMG650ADP-Glo
KIF4ChromokinesinAMG650ADP-Glo
KIF10CENP-EAMG650ADP-Glo
KIF11Eg5ARQ621ADP-Glo
KIF18B/AMG650ADP-Glo
KIF7/AMG650ADP-Glo
KIF20AMKLP2AMG650ADP-Glo
KIF22KidAMG650ADP-Glo
KIF5AKHCAMG650ADP-Glo
KIF18A/AMG650ADP-Glo
KIF23MKLP1AMG650ADP-Glo
KIF19A/AMG650ADP-Glo
VCPP97NMS-873ADP-Glo

Contact Us

We value your inquiries and are here to provide you with tailored solutions for your drug discovery and development needs. Whether you have questions, require more information, or are interested in discussing potential collaborations, our team of experts is just a message away.
Feel free to reach out to us.

We are a CRO service organization, not a hospital




Get a quote

Go top