Our Methyltransferase Assay Services use the MTase-Glo luminescence-based platform to measure methyltransferase enzyme activity with high sensitivity and accuracy. Methyltransferases regulate epigenetic processes by transferring methyl groups to DNA, RNA, and proteins, making them important therapeutic targets in cancer, neurodegeneration, and other diseases.
The MTase-Glo system detects methylation by measuring S-adenosylhomocysteine (SAH) generated during methyl transfer. This provides a quantitative readout of enzyme activity and supports evaluation of inhibitor potency with reliable and reproducible assay performance.
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