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Cell Based Assays

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Expertise in Reporter Gene Assays

Cell-Based Assay Platform
Reporter Gene Assays

At ICE Bioscience, we provide reporter gene assay services for studying gene expression, pathway activity, and cellular regulation. By linking a reporter gene to a regulatory sequence of interest, reporter gene activity can be measured as a functional readout of the associated target pathway.

Reporter gene assay overview

Platform Capabilities
Flexible reporter systems for diverse research programs
01 · CELL LINE SELECTION

A diverse range of cell lines is available for stable or transient transfection formats.

02 · TARGET-SPECIFIC PATHWAYS

Reporter constructs support pathway studies including AP-1, NF-κB, CRE, and ARE signaling.

03 · GPCR SIGNALING

GPCR signaling studies ↗ support the discovery of drugs for metabolic disorders and other therapeutic areas.

04 · IMMUNE RESPONSE

Cytokine activity and immune responses can be measured to support immunotherapy and anti-inflammatory drug development.

05 · NUCLEAR RECEPTORS

Nuclear receptor research ↗ uses custom cell lines to investigate hormone-related disease biology.

06 · DNA DAMAGE RESPONSE

DDR assays ↗, including HR and NHEJ reporter systems, support cancer biology and oncology therapeutic research.

07 · HIGH-THROUGHPUT SCREENING

Reporter systems can support high-throughput screening for the rapid identification of therapeutic compounds.

08 · CUSTOM ASSAY DEVELOPMENT

Customized reporter gene assays can be developed according to specific research requirements.

Reporter gene assay capabilities

Applications
Functional readouts for discovery and biology
01 · DRUG DISCOVERY

Facilitates the identification and validation of new drug targets.

02 · GENE REGULATION

Helps elucidate mechanisms of gene regulation in response to different stimuli.

03 · PATHWAY ANALYSIS

Provides insights into complex cellular signaling pathways.

04 · SAFETY TESTING

Supports cytotoxicity assessment during drug development.

05 · BIOLOGICAL RESEARCH

Supports fundamental biological and disease-oriented research.

ICE Bioscience provides reliable, high-quality reporter gene assay services to support research and development programs.


Contact Us

We value your inquiries and are here to provide you with tailored solutions for your drug discovery and development needs. Whether you have questions, require more information, or are interested in discussing potential collaborations, our team of experts is just a message away.
Feel free to reach out to us.

We are a CRO service organization, not a hospital




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