EN CN


In Vitro Immunology Assays

Return

Biomarker Discovery and Detection

Biomarker Strategy & Translation

At ICE Bioscience, we provide end-to-end biomarker discovery and detection services designed to accelerate drug development and support therapeutic decision-making. From sample collection and processing to biomarker validation and quantification, our platforms and scientific expertise support accurate identification of biomarkers relevant to drug efficacy, safety assessment and patient stratification.

Whether a program is in early-stage discovery or clinical development, our services provide structured, data-driven support across the biomarker pipeline.

Access the biomarker services brochure here ↗.

End-to-End Workflow

Biomarker Discovery and Detection Workflow

01 · Sample Collection

Species: Human, mouse, rat, dog, rabbit and monkey.

Health Status: Healthy and disease-state samples.

Sample Types: Blood, serum, plasma, tissue biopsies, urine, cerebrospinal fluid (CSF) and PBMCs.

02 · Sample Processing and Storage

Processing: Isolation of key components, including cells, plasma and proteins.

Storage: Optimal conditions, including cryopreservation where appropriate, to preserve biomarker stability.

03 · Biomarker Discovery and Profiling

Platform Selection: High-throughput screening, genomics, proteomics and epigenetics platforms.

Technologies: qPCR, sequencing, LC-MS/MS, JESS, ELISA, MSD and other analytical technologies.

04 · Biomarker Validation and Quantification

Validation: Confirmation of biomarker identity, specificity and reproducibility.

Quantification: Multiplex assays including MSD, AlphaLISA and HTRF, together with Western blot and other methods.

05 · Cellular Functional Analysis (Optional)

Flow cytometry, IncuCyte and high-content analysis can be used to assess cellular responses associated with biomarker activity.

06 · In Vivo Imaging (Optional)

Non-invasive imaging of biomarkers in live animal models can be used to monitor disease progression.

07 · Data Analysis and Reporting

Statistical Analysis: Identification of trends, associations and correlations.

Interpretation: Results are contextualized for relevant therapeutic or biological processes.


Contact Us

We value your inquiries and are here to provide you with tailored solutions for your drug discovery and development needs. Whether you have questions, require more information, or are interested in discussing potential collaborations, our team of experts is just a message away.
Feel free to reach out to us.

We are a CRO service organization, not a hospital




Get a quote

Go top