Our cell-based assay platforms are designed to deliver reliable and actionable data, enabling researchers to gain deep insights into cellular responses, molecular interactions, and drug mechanisms of action. Leveraging advanced technologies and methodologies, our platforms provide robust solutions for target validation, compound screening, and toxicity assessment, ultimately accelerating the pace of drug discovery.

MSD (Meso Scale Discovery)

MSD assays use electrochemiluminescence detection technology to measure analytes in biological samples. This technology involves binding analytes to capture antibodies immobilized on the surface of multi-spot plates, followed by detection using electrochemiluminescent tags.

Applications: Multiplex biomarker analysis, cytokine profiling, biomarker validation, pharmacokinetic and pharmacodynamic studies.

Flow Cytometry

Flow cytometry is a technique used to analyze the physical and chemical characteristics of particles as they pass through laser beams in a fluid stream. It measures fluorescence intensity and light scattering properties to identify and characterize cells and particles. 

Applications: Cell surface marker analysis, cell cycle analysis, apoptosis detection, intracellular protein detection, immunophenotyping.

Incucyte (Live-Cell Analysis System)

Incucyte is a live-cell imaging system that enables real-time, automated analysis of cell behavior and morphology over time. It uses phase contrast and fluorescence microscopy to monitor cellular processes within an incubator environment.

Applications: Cell proliferation and viability assays, cell migration and invasion assays, apoptosis and cytotoxicity assays, immune cell activation assays.

Operetta High-Content Screening (HCS)

HCS combines automated microscopy with image analysis algorithms to perform quantitative analysis of cellular features and functions at the single-cell level. It allows for the screening of large compound libraries or siRNA libraries in cellular assays.

Applications: Phenotypic screening, target identification and validation, pathway analysis, toxicity screening, 3D cell culture assays.

FLIPR Penta High-Throughput Cellular Screening

FLIPR assays utilize fluorescence detection to monitor changes in intracellular calcium levels or membrane potential in cultured cells. This technique involves loading cells with fluorescent calcium or voltage-sensitive dyes, followed by fluorescence imaging using a plate reader. Changes in fluorescence intensity indicate alterations in cellular physiology, such as receptor activation or ion channel modulation.

Applications: High-throughput screening (HTS) of G protein-coupled receptor (GPCR) activation, ion channel modulation, compound profiling, drug screening, toxicity testing, and functional characterization of cellular responses.

Jess Automated Western Blot System

JESS simplifies and streamlines the Western blot workflow by utilizing capillary electrophoresis technology combined with immunodetection. It allows for precise and reproducible quantification of protein expression levels in biological samples.

Applications: Automated Western blotting, protein expression analysis, biomarker discovery, drug development research.

In-Cell Western

In-Cell Western assays utilize immunofluorescence detection to measure protein expression levels directly within intact cells. This technique involves the use of fluorescently labeled antibodies to target specific proteins of interest within fixed and permeabilized cells, followed by fluorescence imaging and quantification.

Applications: Protein expression profiling, pathway analysis, quantification of protein-protein interactions, drug target validation, assessment of intracellular signaling pathways.