In vitro T-cell assays are essential for studying T-cell activation, signaling pathways and proliferation in response to defined stimuli. These assays support evaluation of antigen-specific responses, cytokine production and the activity and safety of immunomodulatory drugs. They are also useful for investigating autoimmune disease and cancer mechanisms and for supporting personalized medicine through biomarker discovery and analysis of individual T-cell profiles.
These assays measure T-cell activation in response to different stimuli and support immunology research, immunotherapy development and investigation of immune responses to pathogens.
We provide robust methods for measuring T-cell activation in response to specific antigens, generating insights into immune function and the efficacy of immunotherapies.
T-cell proliferation assays assess the expansion of T cells following stimulation, providing a readout of immune responses in health and disease.
Our services include the in vitro differentiation of naïve CD4+ T cells into Th1, Th2, Th17 and Treg subsets. T-cell receptors are stimulated in the presence of defined cytokines to model T-cell behavior under different immunological conditions.
Regulatory T cells (Tregs), including natural Tregs (nTregs) and induced Tregs (iTregs), are important for maintaining immune balance. Characterized by CD4+, CD25+ and FOXP3+ markers, Tregs are being investigated in autoimmune disease, organ transplantation and cancer. iTregs are derived from naïve T cells through defined stimulation and can suppress other immune cells, supporting evaluation of immunomodulatory therapies.
We guide the differentiation of naïve T cells into Tregs and confirm the resulting phenotype using markers such as CD25 and FOXP3 by flow cytometry. Compounds that may influence Treg polarization can also be evaluated to support investigation of potential therapeutic interventions.
This assay quantitatively evaluates the suppressive capacity of Tregs by measuring their effects on responder T-cell proliferation, including CD4+ or CD8+ effector T cells, under co-culture conditions.
We value your inquiries and are here to provide you with tailored solutions for your drug discovery and development needs. Whether you have questions, require more information, or are interested in discussing potential collaborations, our team of experts is just a message away.
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Address: Bldg 16, Yd 18, Kechuang 13th St, Etown, Tongzhou Dist, Beijing, 100176, China
Email: marketing@ice-biosci.com
Tel：+86-10-67809840
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