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Protein Expression and Purification Services

Custom Protein Services

ICE Bioscience’s Custom Protein Expression and Purification Services are built upon three foundational pillars designed to deliver high-quality proteins for drug discovery. Each module is selected and optimized according to the properties and intended use of the target protein.

For ready-to-use proteins and available product specifications, visit the ICE Bioscience Protein Product Store ↗.

EXPRESSION AND PURIFICATION

Three integrated service pillars

01 · PROTEIN EXPRESSION PLATFORM
E. coli Expression

A fast and cost-effective system for high-yield protein production.

Insect Expression

Used for complex protein production requiring post-translational modifications.

Mammalian Cell Expression

A premium option for producing proteins with human-like post-translational modifications and high biological activity.

Each expression system is selected according to the specific needs of the target protein to support optimal yield and functionality.

02 · PROTEIN PURIFICATION PLATFORM
Manual Affinity Chromatography

Precise and tailored purification for capture of the protein of interest.

AKTA Automation

Automated, high-throughput purification using affinity, ion-exchange, and size-exclusion techniques.

Purification strategies are fine-tuned to the unique properties of each protein to support purity and structural integrity.

03 · QUALITY CONTROL
Routine Tests
SDS-PAGE: Verify protein purity.
SEC-HPLC: Assess molecular-size distribution.
LCMS: Confirm protein mass and identity.
Biophysics and Biochemical Assays
SPR: Monitor protein interactions and kinetics in real time.
TSA: Evaluate protein stability.
Biochemical activity fitting: Quantitatively assess protein function through enzyme-kinetics and binding assays.

Our comprehensive Quality Control Platform ensures that each protein meets stringent quality standards and provides reliable material for functional assays.

PROJECT SUPPORT

Precision and reliability for custom protein projects

Leverage ICE Bioscience’s integrated expression, purification, and quality-control platforms to advance your research with confidence. Our structured approach is designed to provide proteins that meet demanding requirements for drug discovery and functional studies. Contact us to initiate a custom protein project with a partner committed to scientific rigor and quality excellence.


Contact Us

We value your inquiries and are here to provide you with tailored solutions for your drug discovery and development needs. Whether you have questions, require more information, or are interested in discussing potential collaborations, our team of experts is just a message away.
Feel free to reach out to us.

We are a CRO service organization, not a hospital




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