B Cell Assay Services

B cells play a central role in adaptive immunity and are important therapeutic targets in autoimmune disease, inflammation and oncology. ICE Bioscience provides in vitro B cell assay services that evaluate B cell activation, proliferation, differentiation and antibody production, supporting immunology drug discovery programs.

B Cell Assay Capabilities

• B cell isolation and preparation from primary sources
• B cell activation assays following stimulation through BCR, CD40 or TLR pathways
• Proliferation and viability readouts
• Differentiation and antibody (immunoglobulin) secretion assays
• Cytokine and surface marker analysis by flow cytometry

Applications

B cell assays are widely used to profile immunosuppressive and immunomodulatory compounds, evaluate antibody-based therapeutics and investigate mechanisms of action in autoimmune and inflammatory disease models. Assays can be customized to specific project needs, including compound screening and dose-response profiling.

Part of a Complete Immunology Offering

B cell assays at ICE Bioscience are part of a comprehensive in vitro immunology platform that also includes T cell, NK cell, dendritic cell and macrophage assays, enabling multi-lineage immune profiling within a single project.

If you would like to learn more about this service or discuss your project, please contact our team for a tailored proposal and quotation.