Protein Production and Biophysical Assay Services

High-quality protein reagents and reliable biophysical data are essential for modern drug discovery. ICE Bioscience offers integrated protein production and biophysical assay services, taking your project from gene to validated binding data within a single, streamlined workflow.

Protein Production

Our protein sciences team provides recombinant protein expression and purification services across multiple expression systems. Proteins are delivered with defined purity, activity and documentation, ready for use in screening, structural biology and assay development.

Biophysical Assay Services

ICE Bioscience's biophysics platform characterizes molecular interactions and protein stability using a complementary set of label-free technologies:

• Surface Plasmon Resonance (SPR) for binding kinetics and affinity
• Isothermal Titration Calorimetry (ITC) for binding thermodynamics
• Thermal Shift Assay (TSA) and nanoDSF for protein stability
• MST-TRIC and Spectral Shift for in-solution affinity measurement
• Intact mass spectrometry for protein characterization and covalent binding analysis

Applications in Drug Discovery

These services support hit confirmation, lead optimization, fragment screening and mechanism-of-action studies. By combining protein production with biophysical characterization, ICE Bioscience helps clients move from target concept to validated, quantitative binding data efficiently.

If you would like to learn more about this service or discuss your project, please contact our team for a tailored proposal and quotation.