Dendritic Cell (DC) Assay Services

Dendritic cells (DCs) are the most potent antigen-presenting cells of the immune system and a key target for immuno-oncology and autoimmune drug discovery. ICE Bioscience offers in vitro dendritic cell assay services to evaluate DC maturation, antigen presentation and T cell priming, supporting the development of immune-modulating therapeutics.

DC Assay Capabilities

• Monocyte-derived dendritic cell (moDC) generation
• DC maturation assays with surface marker and cytokine readouts
• Antigen uptake and presentation assays
• DC–T cell co-culture assays to assess T cell priming and polarization
• Compound screening for immunostimulatory or immunosuppressive activity

Applications

DC assays are used to evaluate adjuvants, checkpoint modulators, small-molecule immunomodulators and biologics, as well as to study mechanisms of immune activation and tolerance. Readouts typically include flow cytometry phenotyping and cytokine profiling.

Integrated Immunology Platform

DC assays complement ICE Bioscience's broader immunology services — including T cell, B cell, NK cell and macrophage assays — allowing clients to build complete mechanistic pictures of immune-modulating drug candidates.

If you would like to learn more about this service or discuss your project, please contact our team for a tailored proposal and quotation.