Therapeutic Areas

Therapeutic Areas

ICE Bioscience is a leading drug discovery CRO with deep expertise across multiple therapeutic areas. We provide fully integrated drug discovery platforms from target validation to IND-enabling studies, delivering innovative solutions in oncology/immuno-oncology, inflammation and autoimmunity, neuroscience, and metabolic diseases.

Inflammation & Autoimmunity

Our scientists have extensive experience in developing sophisticated in vitro assays using immune cells including PBMCs, T lymphocytes, and phagocytes. We support discovery programs targeting classic and emerging immunology pathways and immune checkpoints. Our capabilities encompass comprehensive assessment of key inflammation and immunological biomarkers, immune cell activation, cytokine release profiling, and T-cell exhaustion studies to advance your immunomodulatory drug candidates.

Metabolic Diseases

ICE Bioscience offers integrated capabilities from hit identification through to in vivo pharmacology and DMPK. Our teams have extensive experience targeting key metabolic pathways including GLP-1R, Amylin and APJ for diseases such as diabetes, NASH, and obesity. We have a proven track record of delivering multiple validated preclinical candidates targeting these high-impact mechanisms to global pharmaceutical partners.

Neuroscience

We possess deep expertise in designing and optimizing CNS-penetrant compounds for neurodegenerative diseases (Alzheimer's, Parkinson's, ALS, multiple sclerosis), antiepileptic, and neuropathic pain. Our integrated platform includes blood-brain barrier models, neuroinflammation assays, electrophysiology, and behavioral pharmacology.

Oncology & Immuno-Oncology

We have successfully delivered multiple preclinical oncology and immuno-oncology programs, from target validation to candidate nomination. Expertise spans small molecules, PROTACs, molecular glues, and antibody-drug conjugates(ADCs) across solid tumors and hematological malignancies, supported by advanced cancer cell panel screening, biomarker discovery, and syngeneic/xenograft studies.

Contact Us

We value your inquiries and are here to provide you with tailored solutions for your drug discovery and development needs. Whether you have questions, require more information, or are interested in discussing potential collaborations, our team of experts is just a message away.
Feel free to reach out to us.

Target Based Assays

Cell Based Assays

Featured Services

In Vitro Safety Assessment

In Vitro Immunology Assays

In Vivo Pharmacology

DMPK

CRO+

Overview