ICE Bioscience provides cutting-edge support for therapeutic discovery leveraging Targeted Protein Degradation (TPD) and the broader realm of Induced Proximity. These transformative platforms enable precise manipulation of protein function through proximity-based mechanisms — from degradation to stabilization, modulation, and more.
We partner with biopharma and academic teams to accelerate drug discovery against historically "undruggable" targets, offering end-to-end expertise in ligand discovery, biochemical/biophysical assay development, cellular validation, and mechanistic insights.
Targeted Protein Degradation (TPD)
From PROTACs, MGDs (molecular glue degraders) to DACs (Degrader-Antibody Conjugates), we support your TPD project development. Our services include degrader screening, complex formation assays, ubiquitination analysis, proteoimcs based off-target profiling, cellular degradation validation and in vivo models.
Explore TPD Services →Induced Proximity (Beyond Degraders)
Unlock the full potential of proximity pharmacology. We provide services for molecular glue screening, proximity-induced stabilization, signaling enhancement — all with a mechanistic-first approach.
Explore Induced Proximity Services →Whether you're focused on protein degradation or exploring alternative proximity-based mechanisms, ICE Bioscience is your scientific partner in navigating the next frontier of drug discovery.
