Natural Killer (NK) Cell Assay Services

Natural killer (NK) cells are critical effectors of innate immunity and an increasingly important focus of immuno-oncology drug development. ICE Bioscience provides NK cell assay services that measure NK cell activation, cytokine production and tumor cell killing, supporting the evaluation of antibodies, engagers and small-molecule immunomodulators.

NK Cell Assay Capabilities

• NK cell isolation and preparation from peripheral blood
• NK cell activation assays with phenotypic and functional readouts
• Cytotoxicity assays against tumor target cells
• Antibody-dependent cellular cytotoxicity (ADCC) assays
• Cytokine release and degranulation measurements

Applications

NK cell assays are widely applied in the development of therapeutic antibodies, bispecific engagers and NK-directed immunotherapies, as well as in safety evaluation of immune-modulating compounds. Assays can be tailored to specific target antigens and effector-to-target ratios.

Complete Immune Effector Profiling

NK cell assays are part of ICE Bioscience's integrated immunology platform, which also covers T cell, B cell, dendritic cell and macrophage assays, enabling comprehensive immune effector profiling for your immuno-oncology programs.

If you would like to learn more about this service or discuss your project, please contact our team for a tailored proposal and quotation.