Chemotaxis Assay Services

Chemotaxis — the directed migration of cells along chemokine gradients — is fundamental to immune cell trafficking, inflammation and tumor immune infiltration. ICE Bioscience provides chemotaxis assay services that quantify immune cell migration in response to chemokine signals, supporting drug discovery in inflammation, autoimmune disease and immuno-oncology.

Chemotaxis Assay Capabilities

• Transwell migration assays for immune and tumor cells
• Chemokine gradient-driven migration readouts
• Compound inhibition or enhancement of cell migration
• Receptor-specific chemotaxis assays (e.g., chemokine receptor antagonist evaluation)
• Dose-response and IC50 profiling

Applications

Chemotaxis assays are widely used to evaluate chemokine receptor antagonists, anti-inflammatory compounds and immunomodulatory biologics, as well as to study mechanisms of immune cell recruitment to tissues and tumors.

Part of an Integrated Immunology Platform

Chemotaxis assays complement ICE Bioscience's full range of immune cell function assays, including activation, proliferation, cytotoxicity and cytokine profiling, providing a comprehensive view of compound effects on immune cell behavior.

If you would like to learn more about this service or discuss your project, please contact our team for a tailored proposal and quotation.