ICE Bioscience combines whole-cell patch clamp with complementary field-potential recording in viable brain slices. The platform measures neuronal excitability, synaptic transmission, receptor-mediated currents and circuit-level activity while retaining the local cellular organization of the selected brain region.
Spontaneous and evoked action potentials provide direct assessment of neuronal firing and compound-induced changes in excitability.
Recordings include sEPSC/sIPSC, mEPSC/mIPSC and eEPSC/eIPSC, together with NMDA, AMPA and GABAA receptor-mediated currents.
LTP, LTD, extracellular field potentials and epileptiform activity support evaluation of plasticity and local circuit function.
Evaluate compound effects in models relevant to neurodegeneration, cerebral ischemia, depression and epilepsy.
Assess compound effects on neuronal firing and epileptiform activity to support functional seizure-risk evaluation.
We value your inquiries and are here to provide you with tailored solutions for your drug discovery and development needs. Whether you have questions, require more information, or are interested in discussing potential collaborations, our team of experts is just a message away.
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Address: Bldg 16, Yd 18, Kechuang 13th St, Etown, Tongzhou Dist, Beijing, 100176, China
Email: marketing@ice-biosci.com
Tel：+86-10-67809840
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