Several ion channels are implicated in disorders of the central and peripheral nervous systems, including ischemic stroke, Alzheimer’s disease and multiple sclerosis. These channels represent important therapeutic targets for neuroprotection, reduction of neuronal damage and management of neurodegenerative symptoms.
Our neurodegeneration–stroke ion channel portfolio is a curated collection of ion channels implicated in the treatment and etiology of neurodegenerative diseases and stroke. The panel supports evaluation of compound target specificity and potential off-target effects, helping researchers investigate mechanisms relevant to neurodegenerative conditions and stroke-related complications.
By integrating targets involved in neuronal excitability, excitatory neurotransmission, ion homeostasis and cellular signaling, the portfolio provides a focused framework for early-stage drug discovery and ion-channel profiling.
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