Our Intact-MS service provides a label-free, high-resolution approach for analyzing the molecular integrity, modifications, and binding-related changes of biomolecules in drug discovery. The method is particularly suited for evaluating covalent binding, structural heterogeneity, and post-translational modifications (PTMs).
Intact-MS measures the mass-to-charge ratio (m/z) of ions to determine the molecular weight of intact proteins or protein complexes without prior enzymatic digestion. By preserving the intact molecular form, the method enables comprehensive analysis of protein composition and modifications.
Mass spectrometry platform ↗ enables detection and quantification of covalent modifications, including small-molecule adducts on target proteins, supporting characterization of covalent inhibitors.
Identifies and characterizes post-translational modifications such as phosphorylation, glycosylation, and acetylation, providing insights into protein structure and activity.
Provides high-precision measurements of intact protein mass to support target identity and purity assessment in drug discovery.
Q Exactive™ Plus Mass Spectrometer
We value your inquiries and are here to provide you with tailored solutions for your drug discovery and development needs. Whether you have questions, require more information, or are interested in discussing potential collaborations, our team of experts is just a message away.
Feel free to reach out to us.
Address: Bldg 16, Yd 18, Kechuang 13th St, Etown, Tongzhou Dist, Beijing, 100176, China
Email: marketing@ice-biosci.com
Tel：+86-10-67809840
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